PolTools

PolTools is a collection of bioinformatic programs analyzing PRO-Seq, PRO-Cap, and similar next generation sequencing experiments analyzing nascent RNAs.

It is primary written in python3, but utilizes R for plotting and C++ for computationally expensive analyses. These tools were developed in the Price Lab.

Please see the documentation for more information.

PolTools contains 19 main programs, listed below. However, PolTools is much more than a collection of bioinformatic programs. It contains an extensive library of utility functions which can easily be used to create new, exciting bioinformatic tools.

• TES Fold Change Heatmap
• TES Heatmap
• Base Distribution
• Gene Body Fold Change Heatmap
• Gene Body Heatmap
• Make Regions File Centered on Max TSS
• Metaplot
• Multicoverage
• Nucleotide Heatmap
• Pausing Distance Distribution from Max TSS
• Read Through Transcription
• Region Fold Change Heatmap
• Region Heatmap
• Sequence from Around Max TSS
• Sequence Searches
• TPS Distance Per Gene
• Track Links From Bigwigs
• truQuant
• tsrFinder