kleborate

Kleborate: a tool for typing and screening pathogen genome assemblies


License
Other
Install
pip install kleborate==3.0.0

Documentation

Kleborate logo

Kleborate v3 includes a rewrite of Kleborate. It aims to:

  • Modularise the code for easier extensibility and maintenance
  • Provide functionality for other species, e.g. Klebsiella oxytoca and Escherichia coli
  • Replace the BLAST dependency with minimap2

Available modules for Kleborate v3:

  • Basic contigs stats
  • Mash-based species detection for Klebsiella and closely-related genera
  • MLST on the KpSC aerobactin locus (iuc genes)
  • MLST on the KpSC colibactin locus (clb genes
  • MLST on the KpSC Rmp locus (rmp genes)
  • MLST on the KpSC salmochelin locus (iro genes)
  • MLST on the KpSC yersiniabactin locus (ybt and irp genes)
  • Chromosomal MLST for Escherichia coli using the Achtman scheme
  • Chromosomal MLST for Escherichia coli using the Pasteur scheme
  • Chromosomal MLST for the Klebsiella oxytoca species complex
  • Chromosomal MLST for the Klebsiella pneumoniae species complex
  • Virulence score (0-5) for the Klebsiella pneumoniae species complex, based on the results of the abst, cbst and ybst modules
  • Genotyping acquired genes and mutations for the Klebsiella pneumoniae species complex
  • Resistance score (0-3) for the Klebsiella pneumoniae species complex, based on the results of the kpsc_amr module
  • Resistance gene classes count
  • Resistance genes count
  • Wzi typing for K antigen prediction
  • Module to call Kaptive for K (capsule) and O antigen (LPS) serotype prediction

For information on how to install, and run Kleborate v3 please visit the Docs.