A python package for the automated construction of chimeras and analysis


Keywords
PROTEIN, DESIGN, CHIMERAGENESIS, EVOLUTION, NETWORK, THEORY, FUZZLE
License
Other
Install
pip install protlego==1.0.12

Documentation

protlego

Installation

Protlego can be installed via github, pip, or conda.

PIP installation

To install protlego via pip, just type the following command:

pip install protlego

Taking into account that graph-tool is not included in Pypi, you will need to install it separately. To do so, please refer to the graph-tool documentation: https://git.skewed.de/count0/graph-tool/-/wikis/installation-instructions

CONDA installation

To install protlego via conda, type the following:

conda install -c nferruz protlego

You will need to adjust the boost installation after installing. Type:

conda install -c anaconda boost=1.69

Also make sure your cairo package comes from channel conda-forge. If it is not, you can type:

conda install -c conda-forge cairo

Once the environment installed, you can start designing chimeras with protlego!

Setup

You will need a Fuzzle database. Download the latest version from here:

https://132.180.65.101/static/js/hh207clusters.csv.

Then go to your protlego folder, and run the script

python database/database_setup.py.

Make sure you have changed the path to your hh207clusters.csv accordingly.