ExonViz is a simple tool to generate and draw transcripts that include coding and non-coding regions. All exons are to scale and the reading frames of the exons are visible. Single or multiple variants along the transcript can be drawn and will automatically be shown in the correct location.

You can try out ExonViz online at exonviz.rnatherapy.nl.

ExonViz only requires Python, and can be installed using PIP:

pip install exonviz

Simply supply either a transcript (with version!), or a valid HGVS description to exonviz to generate a figure:

exonviz --transcript "NM_003002.4:r.[274G>T;300del]" > SHDH.svg

The documentation for ExonViz is available on Readthedocs, including some examples of what is possible using the command line version of ExonViz.