sterope

Sterope: Sensitivity analysis of kappa Rule-Based Models based on Dynamic Influence Networks


Keywords
systems, biology, stochastic, modeling, parameter, analysis
License
GPL-3.0+
Install
pip install sterope==1.5

Documentation

sterope

Sterope is a python3 package that implement a method based on the Dynamic Influence Network (https://www.ncbi.nlm.nih.gov/pubmed/28866584) to analyze the sensitivity of parameter values in the response of a Rule-Based Model written in kappa (https://kappalanguage.org/)

The plan to add methods into Pleiades (https://github.com/glucksfall/pleiades) includes a parameterization employing a Particle Swarm Optimization protocol and other analysis methods that are typical of frameworks like Ordinary Differential Equations. You could write us if you wish to add methods into pleione or aid in the development of them.